Ion Chromatography and its applications


Ion chromatography (IC) is a technique for the separation and detection of ionic species or ionizable compounds. It is one type of liquid chromatography which employs ion-exchange or ion exclusion stationary phases for separation. Conductivity is mainly used for detection while UV, amperometry, mass spectroscopy or other techniques are also used for detection. Ion chromatography is widely used in the analysis and the purification of ionic or ionizable compounds.


Ion Chromatography is often used for the analysis in the pharmaceutical, biological, chemical, environmental, industrial, and food industries. A wide range of samples may be analyzed including inorganic cations/anions, organic bases/acids, ionizable surfactants, amino acids, peptides, saccharide and conjugates, proteins, DNA/RNA, and other ionic or ionizable compounds.


Pine Labs may provide Method development and Analysis of Ionic and Polar Compounds:

  • Inorganic and organic anions
  • Inorganic and organic cations
  • Amino acids, proteins and peptides
  • Zwitter ions such as surfactants
  • Carbohydrates, oligosaccharides and polysaccharides
  • RNA and DNA oligonucleotides
  • Polar Compounds: alcohols, aldehydes, phenols, organic acids, amines, surfactants, carboxylates, polyphosphates, and etc.